Hsp90 webinars 2020-2021

June 18, 2020

Johannes Buchner (Technische Universität München, Garching, Germany)

The Hsp90 chaperone machinery – old traits and new features

I watch my chaperon’s face,
And see the dear old features take
A new and tender grace   (Henry Cuyler Bunner)

July 16, 2020

Len Neckers (NCI-NIH, Bethesda MD, USA)

TRAP1 Function: Evidence that a mitochondrial matrix chaperone can re-wire cellular metabolism

August 18, 2020

Judy Frydman (Stanford, Palo Alto CA, USA)

Hsp90 shapes the evolution of RNA viruses

September 14, 2020

David Agard (UCSF, San Francisco CA, USA)

To fold or not to fold: the mechanism of chaperone-mediated client activation revealed in atomic detail

October 15, 2020

Leah Cowen (University of Toronto, Canada)

Targeting Hsp90 to cripple fungal pathogens

November 23, 2020

Didier Picard (University of Geneva, Switzerland)

Short vignettes of history, knockouts, interactors, cancer, and tetramers

January 19, 2021

Gabriela Chiosis (Memorial Sloan Kettering Cancer Center, New York, USA)

Epichaperomes – from function to detection and targeting

February 23, 2021

Mehdi Mollapour (SUNY Upstate Medical University, Syracuse, NY, USA)

Post-translational modifications of Hsp90 and translating the chaperone code

March 10, 2021

Brian S. J. Blagg (University of Notre Dame, IN, USA)

Unforeseen opportunities to modulate cancer and the CNS with isoform-selective inhibitors of Hsp90

April 15, 2021

Patricija van Oosten-Hawle (University of Leeds, UK)

Beyond the cellular boundary: How inter-tissue signaling regulates organismal chaperone expression in C. elegans

May 11, 2021

Brian C. Freeman (University of Illinois, Urbana, IL, USA)

Expanding the Hsp90 physical interactome: an Hsp90 role in nascent chain production?

June 15, 2021

Stefan Rüdiger (Utrecht University, Netherlands)

Hsp90 in protein folding

July 28, 2021

Stephanie Diezmann (University of Bristol, UK)

Hsp90’s role in Candida biology and virulence

September 7, 2021

Vincent S. Tagliabracci (UT Southwestern Medical Center, Dallas, TX, USA)

A bacterial effector mimics a host HSP90 client to undermine immunity

October 18, 2021

Matthias P. Mayer (Zentrum für Molekulare Biologie der Universität Heidelberg, Germany)

Regulation of the conformation of human Hsp90

November 23, 2021

Luke L. Lairson (The Scripps Research Institute, La Jolla, CA, USA)

HSP90 inhibition modulates the expression of multiple immune checkpoint proteins