Hsp90 webinars
Proposed by the organizers and advisory committee of the meeting series on the “Hsp90 chaperone machine”. Online seminars by zoom are held roughly once a month on a weekday at 6 pm CET (Geneva-Munich)/9 am PST (apologies to our Hsp90 friends in places like the Far East/Australia). Talks will be regular full seminars (~45 minutes) with the possibility to ask questions after the presentation. Talks are NOT recorded.
The webinars are free, but advanced registration for the webinar series is required to obtain further information and the zoom links for the individual webinars.
The detailed program is listed here for the next few months (stay tuned for updates and extensions).
June 18, 2020
Johannes Buchner (Technische Universität München, Garching, Germany)
The Hsp90 chaperone machinery – old traits and new features
I watch my chaperon’s face,
And see the dear old features take
A new and tender grace
(Henry Cuyler Bunner)
July 16, 2020
Len Neckers (NCI-NIH, Bethesda MD, USA)
TRAP1 Function: Evidence that a mitochondrial matrix chaperone can re-wire cellular metabolism
August 18, 2020
Judy Frydman (Stanford, Palo Alto CA, USA)
Hsp90 shapes the evolution of RNA viruses
September 14, 2020
David Agard (UCSF, San Francisco CA, USA)
To fold or not to fold: the mechanism of chaperone-mediated client activation revealed in atomic detail
October 15, 2020
Leah Cowen (University of Toronto, Canada)
Targeting Hsp90 to cripple fungal pathogens
November 23, 2020
Didier Picard (University of Geneva, Switzerland)
Short vignettes of history, knockouts, interactors, cancer, and tetramers
January 19, 2021
Gabriela Chiosis (Memorial Sloan Kettering Cancer Center, New York, USA)
Epichaperomes – from function to detection and targeting
February 23, 2021
Mehdi Mollapour (SUNY Upstate Medical University, Syracuse, NY, USA)
Post-translational modifications of Hsp90 and translating the chaperone code
March 10, 2021
Brian S. J. Blagg (University of Notre Dame, IN, USA)
Unforeseen opportunities to modulate cancer and the CNS with isoform-selective inhibitors of Hsp90
April 15, 2021
Patricija van Oosten-Hawle (University of Leeds, UK)
Beyond the cellular boundary: How inter-tissue signaling regulates organismal chaperone expression in C. elegans
May 11, 2021
Brian C. Freeman (University of Illinois, Urbana, IL, USA)
Expanding the Hsp90 physical interactome: an Hsp90 role in nascent chain production?
June 15, 2021
Stefan Rüdiger (Utrecht University, Netherlands)
Hsp90 in protein folding
July 28, 2021
Stephanie Diezmann (University of Bristol, UK)
Hsp90’s role in Candida biology and virulence
September 7, 2021
Vincent S. Tagliabracci (UT Southwestern Medical Center, Dallas, TX, USA)
A bacterial effector mimics a host HSP90 client to undermine immunity
October 18, 2021
Matthias P. Mayer (Zentrum für Molekulare Biologie der Universität Heidelberg, Germany)
Regulation of the conformation of human Hsp90
November 23, 2021
Luke L. Lairson (The Scripps Research Institute, La Jolla, CA, USA)
HSP90 inhibition modulates the expression of multiple immune checkpoint proteins